基因组印记。有甲基化和无甲基化的印记。
Genomic imprinting. Imprinting with and without methylation.
作者信息
Reik W, Allen N D
机构信息
Laboratory of Developmental Genetics and Imprinting, AFRC Babraham Institute, Cambridge, U.K.
出版信息
Curr Biol. 1994 Feb 1;4(2):145-7. doi: 10.1016/s0960-9822(94)00034-5.
PMID:7953517
Abstract
Methyltransferase-deficient mice reveal that DNA methylation is required for the somatic-cell maintenance of parental imprinting, which alters the expression of a gene according to the parent from which it was inherited.
摘要
甲基转移酶缺陷型小鼠表明，DNA甲基化是亲本印记体细胞维持所必需的，亲本印记会根据基因的遗传亲本改变基因的表达。
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