Jakobovits A
Department of Molecular Immunology, Cell Genesys Inc., Foster City, California 94404.
Curr Biol. 1994 Aug 1;4(8):761-3. doi: 10.1016/s0960-9822(00)00172-x.
The ability to replace mouse genes with their human equivalents using "yeast artificial chromosome" technology provides a powerful new technique for studying the regulation and function of human genes.