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一例罕见的转移性心脏浆细胞瘤病例。

An unusual case of metastatic intracardiac plasmacytoma.

作者信息

Tak T, Rashtian M, De Tar M, Chandraratna P A, Gill P

机构信息

Department of Medicine, LAC+USC Medical Center 90033.

出版信息

Can J Cardiol. 1994 Oct;10(8):857-60.

PMID:7954022
Abstract

The authors report the case of a 36-year-old male who, following investigations for dyspnea, othopnea and peripheral cyanosis, was found to have metastatic intracardiac plasmacytoma. Diagnosis was made initially with transesophageal echocardiography and emergent cardiac surgery was performed. Postoperative transthoracic and transesophageal echocardiograms revealed residual masses in the right and left atrium. The patient was subsequently treated with systemic chemotherapy and was symptom-free within three months of treatment, with rapid decline of paraproteins in the serum and urine. This case of intracardiac metastatic plasmacytoma is deemed unique because cardiac involvement with multiple myeloma has not been studied in detail, largely due to the rarity of such a presentation.

摘要

作者报告了一例36岁男性病例,该患者在因呼吸困难、端坐呼吸和外周发绀接受检查后,被发现患有转移性心内浆细胞瘤。最初通过经食管超声心动图做出诊断,并进行了急诊心脏手术。术后经胸和经食管超声心动图显示右心房和左心房有残留肿块。该患者随后接受了全身化疗,治疗后三个月内症状消失,血清和尿液中的副蛋白迅速下降。这例心内转移性浆细胞瘤病例被认为是独特的,因为多发性骨髓瘤累及心脏尚未得到详细研究,主要是由于这种表现非常罕见。

相似文献

1
An unusual case of metastatic intracardiac plasmacytoma.一例罕见的转移性心脏浆细胞瘤病例。
Can J Cardiol. 1994 Oct;10(8):857-60.
2
Clinical relapse in a patient with multiple myeloma presenting as an atrial plasmacytoma.
J Clin Oncol. 2011 Jan 20;29(3):e47-9. doi: 10.1200/JCO.2010.30.3370. Epub 2010 Oct 18.
3
Usefulness of transesophageal echocardiographic observation during chemotherapy for cardiac metastasis of non-Hodgkin lymphoma complicated with left ventricular diastolic collapse.经食管超声心动图观察在化疗治疗非霍奇金淋巴瘤合并左心室舒张性崩溃的心脏转移中的作用。
J Cardiol. 2009 Jun;53(3):447-52. doi: 10.1016/j.jjcc.2008.08.009. Epub 2008 Oct 14.
4
[Advantages of transesophageal color Doppler echocardiography in the diagnosis and surgical treatment of cardiac masses].经食管彩色多普勒超声心动图在心脏肿物诊断及外科治疗中的优势
J Cardiol. 1990;20(3):701-14.
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A rare case of primitive right atrium angio-sarcoma with favorable outcome, in a young female. Case report and literature review.一名年轻女性原发性右心房血管肉瘤的罕见病例及良好预后。病例报告与文献综述。
Rev Med Chil. 2008 Oct;136(10):1311-6. Epub 2009 Jan 15.
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Tricuspid valve obstruction caused by plasmacytoma metastasis.浆细胞瘤转移引起的三尖瓣梗阻
Ann Thorac Surg. 1992 Aug;54(2):352-4. doi: 10.1016/0003-4975(92)91399-t.
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[Contribution of transesophageal echocardiography in the diagnosis of intra- and para-cardiac masses].[经食管超声心动图在心脏内及心脏旁肿物诊断中的作用]
Arch Mal Coeur Vaiss. 1993 Mar;86(3):331-8.
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Contrast echocardiography as a useful additional diagnostic tool in evaluating a primary cardiac tumor.对比增强超声心动图作为评估原发性心脏肿瘤的一种有用的辅助诊断工具。
Eur J Echocardiogr. 2005 Oct;6(5):388-91. doi: 10.1016/j.euje.2005.02.002. Epub 2005 Apr 2.
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[Cardiac metastasis of a plasmacytoma with clinical manifestations of an extensive pulmonary embolism. Obstruction of the right ventricular outflow tract].[浆细胞瘤的心脏转移伴广泛肺栓塞的临床表现。右心室流出道梗阻]
Dtsch Med Wochenschr. 1998 Nov 13;123(46):1372-7. doi: 10.1055/s-2007-1024190.
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Metastatic involvement of the left atrium revealed by electrocardiographic Ta segment change.
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引用本文的文献

1
Cardiac plasmacytoma: a rare clinical entity.心脏浆细胞瘤:一种罕见的临床实体。
Tex Heart Inst J. 2014 Oct 1;41(5):554-7. doi: 10.14503/THIJ-13-3436. eCollection 2014 Oct.
2
Myeloma and a mass in the heart.骨髓瘤与心脏肿物
J R Soc Med. 2003 Jun;96(6):288-9. doi: 10.1177/014107680309600608.