Chi L H, Wu C W, Hsieh M C, Tsay S H, Lui W Y
Department of Surgery, Veterans General Hospital-Taipei, Taiwan, R.O.C.
Zhonghua Yi Xue Za Zhi (Taipei). 1994 Aug;54(2):111-5.
Gastric cancer invading the lamina muscularis propria is considered to be an intermediate stage between early and far advanced gastric cancer. This study evaluated the clinicopathological pictures of muscularis propria gastric cancer.
In the past 5 years, 407 patients with adenocarcinoma of stomach underwent radical gastrectomy in Department of Surgery, Veterans General Hospital-Taipei. Of them, 46 patients (11.3%) with gastric cancer invading the muscularis propria were studied. Their clinicopathologic features were further analyzed with special reference to the gross appearance of the tumor.
Most muscularis propria gastric cancers occurred at lower stomach. Nodal spread accounted for 32.6% and was largely confined to n2 with limited involvement of n3. Borrmann type cancer comprised 63% (29/46) of cases and early-like type cancer comprised 37%. Early-like type cancer was smaller in size than Borrmann type cancer (p < 0.001). Nodal spread was more extent in Borrmann type cancer than in early-like type cancer. Other clinicopathologic features and survival were identical in both types of muscularis propria gastric cancer.
Most muscularis propria gastric cancers were Borrmann type cancer grossly. Compared with the early-like type, the Borrmann type cancer was larger and had more extensive nodal spread.
侵犯固有肌层的胃癌被认为是早期胃癌和进展期胃癌之间的中间阶段。本研究评估了固有肌层胃癌的临床病理特征。
在过去5年中，台北荣民总医院外科对407例胃腺癌患者进行了根治性胃切除术。其中，对46例（11.3%）侵犯固有肌层的胃癌患者进行了研究。特别参照肿瘤的大体外观，进一步分析了他们的临床病理特征。
大多数固有肌层胃癌发生在胃下部。淋巴结转移占32.6%，主要局限于n2，n3受累有限。Borrmann型癌占病例的63%（29/46），类早期癌占37%。类早期癌的大小小于Borrmann型癌（p < 0.001）。Borrmann型癌的淋巴结转移程度比类早期癌更广泛。两种类型的固有肌层胃癌的其他临床病理特征和生存率相同。
大多数固有肌层胃癌大体上为Borrmann型癌。与类早期癌相比，Borrmann型癌更大，淋巴结转移更广泛。
