肾素分泌瘤所致继发性高血压：一例报告

Secondary hypertension due to renin secreting tumor: a case report.

作者信息

Chung C T, Chen J W, Wu T R, Chen K K, Wang J H, Yang A H, Chang M S

机构信息

Department of Medicine, Veterans General Hospital-Taipei, Taiwan, R.O.C.

出版信息

Zhonghua Yi Xue Za Zhi (Taipei). 1994 Sep;54(3):188-92.

PMID:7954061

Abstract

We report a 20-year-old female with severe hypertension, hypokalemia, hyperaldosteronism and elevated level of plasma renin activity (PRA). The clinical diagnosis of renin secreting tumor of left kidney was made before surgery by the lateralization of plasma renin activity via selective renal venous blood sampling and CT scan of kidney. Prompt normalization of blood pressure and decrease of PRA and aldosterone levels were found after surgical removal of the tumor. The pathological findings showed a juxtaglomerular cell tumor.

摘要

我们报告了一名20岁女性，患有严重高血压、低钾血症、醛固酮增多症以及血浆肾素活性（PRA）升高。术前通过选择性肾静脉血采样测定血浆肾素活性的侧别定位以及肾脏CT扫描，临床诊断为左肾肾素分泌肿瘤。手术切除肿瘤后，血压迅速恢复正常，PRA和醛固酮水平降低。病理检查结果显示为肾小球旁细胞瘤。