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一种用于评估脑脊液分流系统的非线性生物力学模型。

A nonlinear biomechanical model for evaluation of cerebrospinal fluid shunt systems.

作者信息

Hafez M A, Kempski O

机构信息

Department of Neurosurgery, Cairo University, Egypt.

出版信息

Childs Nerv Syst. 1994 Jul;10(5):302-10; discussion 310-1. doi: 10.1007/BF00335168.

Abstract

In view of complications arising from physical properties of cerebrospinal fluid shunts, a biomechanical model of hydrocephalus was set up to study in vivo parameters that may influence their function. These include: intracranial pressure, compliance and pulses, intrathoracic, intra-abdominal, and subcutaneous pressures, and the effects of siphonage and repeated valve flushing. Each of these factors was studied separately upon shunt implantation in the model. Results of testing of a sample low-pressure valve with antisiphon device conformed with consumer information in regard to valve opening pressure and pressure flow measurements. No customer information, however, was supplied concerning the deleterious effects of direct subcutaneous pressure, variable degrees of siphonage, and repeated valve flushing that were demonstrated by the model. Such results indicate that shunts should be similarly tested prior to marketing and implantation in patients.

摘要

鉴于脑脊液分流器物理特性引发的并发症,建立了脑积水生物力学模型,以研究可能影响其功能的体内参数。这些参数包括:颅内压、顺应性和脉搏、胸腔内、腹腔内和皮下压力,以及虹吸作用和反复冲洗阀门的影响。在模型中植入分流器时,对上述每个因素都进行了单独研究。对一个带有抗虹吸装置的样本低压阀门进行测试的结果,在阀门开启压力和压力流量测量方面与用户信息相符。然而,未提供任何关于直接皮下压力、不同程度的虹吸作用以及模型所显示的反复冲洗阀门的有害影响的用户信息。这些结果表明,分流器在上市销售和植入患者体内之前,应进行类似的测试。

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