急性脑梗死中地塞米松与低分子右旋糖酐联合应用：双盲研究
Combined dexamethasone and low-molecular-weight dextran in acute brain infarction: double-blind study.
作者信息
Kaste M, Fogelholm R, Waltimo O
出版信息
Br Med J. 1976 Dec 11;2(6049):1409-10. doi: 10.1136/bmj.2.6049.1409.
Abstract
Intramuscular dexamethasone combined with intravenous low-molecular-weight dextran (dextran 40) was compared with placebo in 40 patients with acute ischaemic cerebral infarction. A double-blind procedure was used. Dexamethasone was given for up to 14 days and dextran 40 for up to three days after the infarction. A weighted scoring system was used to evaluate neurological state and mobility. There were no differences in mortality or in improvement of the neurological or mobility scores between the two groups.
摘要
将40例急性缺血性脑梗死患者的肌肉注射地塞米松联合静脉注射低分子右旋糖酐（右旋糖酐40）与安慰剂进行比较。采用双盲程序。梗死发生后，地塞米松给药长达14天，右旋糖酐40给药长达3天。使用加权评分系统评估神经状态和活动能力。两组之间的死亡率以及神经或活动能力评分的改善情况均无差异。
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