Smith R A, Ross J S, Bunker C B
Department of Dermatology, Westminster and Chelsea Hospital, London, UK.
Clin Exp Dermatol. 1994 Sep;19(5):441-2. doi: 10.1111/j.1365-2230.1994.tb02707.x.
Trichorrhexis nodosa is a disorder of the hair shaft in which there is a distinctive response to injury. The hair is fragile and on examination regularly spaced pale 'node-like' swellings may be observed. It may affect normal hair following excessive or repeated trauma, or may occur after minimal trauma if there is an inherent defect in keratin synthesis causing abnormally brittle hair. The diagnosis can be readily made clinically and confirmed microscopically. Treatment is aimed at reducing trauma. We describe a case of localized trichorrhexis nodosa in a patient with otherwise apparently normal hair.
结节性脆发病是一种毛干疾病,其对损伤有独特的反应。毛发很脆弱,检查时可经常观察到有规则间隔的淡色“结节样”肿胀。它可能在过度或反复创伤后影响正常毛发,或者如果角蛋白合成存在内在缺陷导致毛发异常脆弱,那么在轻微创伤后也可能发生。临床诊断容易做出,显微镜检查可予以证实。治疗旨在减少创伤。我们描述了一例局部结节性脆发病患者,其其他部位毛发外观明显正常。