McDermott V G, Merrick M V
Department of Nuclear Medicine, Western General Hospital, Edinburgh.
Clin Radiol. 1994 Oct;49(10):705-7. doi: 10.1016/s0009-9260(05)82665-0.
A retrospective review was performed of 100 enuretic children who underwent isotope renography during the period 1981-1989. Studies performed were Tc99mDMSA studies for renal size and to detect renal scarring and renography using Tc99mDTPA or MAG3 to evaluate excretion and detect vesicoureteric reflux. Fifty-five children had microbiological evidence of urinary tract infection (UTI), and 16 (29%) of these had abnormalities on their isotope studies. Forty-five had sterile urine and all had normal isotope studies. Thus despite recent reports of urodynamic abnormalities and increased incidence of reflux in patients with enuresis, our findings indicate that standard nuclear medicine renal studies show few abnormalities in patients with monosymptomatic enuresis. The 29% incidence of abnormal studies in patients with enuresis and UTIs suggests that the presence of infection should be an indication for further investigation in this subgroup of enuretic children.
对1981年至1989年期间接受同位素肾图检查的100例遗尿症儿童进行了回顾性研究。所进行的检查包括用99m锝二巯基丁二酸（Tc99mDMSA）检查肾脏大小和检测肾瘢痕，以及用99m锝二乙三胺五醋酸（Tc99mDTPA）或巯基乙酰三甘氨酸（MAG3）进行肾图检查以评估排泄功能和检测膀胱输尿管反流。55例儿童有泌尿系统感染（UTI）的微生物学证据，其中16例（29%）同位素检查有异常。45例尿液无菌，所有同位素检查均正常。因此，尽管最近有报道称遗尿症患者存在尿动力学异常和反流发生率增加，但我们的研究结果表明，标准的核医学肾脏检查显示单症状性遗尿症患者很少有异常。遗尿症合并UTI患者检查异常的发生率为29%，这表明感染的存在应作为对这一亚组遗尿症儿童进一步检查的指征。
