Dominguez-Gadea L, Diez L, Bas C, Crespo A
Nuclear Medicine Service, Hospital Ramón y Cajal, Madrid, Spain.
Clin Radiol. 1994 Nov;49(11):796-9. doi: 10.1016/s0009-9260(05)81970-1.
To evaluate the diagnostic contribution of adrenal scintigraphy with 75-Se-selenomethylcholesterol in adrenal masses, 42 patients have been studied. All of them had a solid adrenal mass discovered on computed tomography (seven bilateral). None of the patients showed any symptoms or clinical signs that might indicate the existence of adrenal dysfunction. Twenty-nine of them had known extra-adrenal primary malignant disease. Forty-nine adrenal tumours were detected with an average size of 3.29 cm (range 1.5-12 cm). Eighteen lesions showed increased uptake of radiocholesterol on the side of the adrenal mass, all of which were either proven to be benign, or behaved in a benign fashion. Twelve lesions showed normal uptake (10 in the benign group and one lung carcinoma metastasis), all but one (2.5 cm) being smaller than 2 cm. Decreased uptake was observed in 20 lesions (15 metastases, two nonfunctional adrenal carcinomas, one myelolipoma and two tuberculous infectious lesions). Adrenocortical scintigraphy provides functional information about adrenal masses and is useful in differentiating between benign and malignant lesions.
为评估75-硒-硒代甲基胆固醇肾上腺闪烁显像对肾上腺肿块的诊断价值，对42例患者进行了研究。所有患者均在计算机断层扫描中发现有肾上腺实性肿块（7例为双侧性）。所有患者均无任何可能提示肾上腺功能障碍存在的症状或临床体征。其中29例患者已知患有肾上腺外原发性恶性疾病。共检测到49个肾上腺肿瘤，平均大小为3.29 cm（范围1.5 - 12 cm）。18个病灶在肾上腺肿块侧显示放射性胆固醇摄取增加，所有这些病灶均被证实为良性或表现为良性。12个病灶摄取正常（良性组10个，1个为肺癌转移灶），除1个（2.5 cm）外，其余均小于2 cm。20个病灶摄取减少（15个转移灶、2个无功能肾上腺皮质癌、1个肾上腺髓质脂肪瘤和2个结核感染病灶）。肾上腺皮质闪烁显像可提供肾上腺肿块的功能信息，有助于鉴别良性和恶性病变。
