Backman C, Jacobsson K A, Linderholm H, Osterman G
Department of Clinical Physiology, University of Umeå, Sweden.
Clin Physiol. 1994 Jul;14(4):475-85. doi: 10.1111/j.1475-097x.1994.tb00406.x.
We have previously found a statistically significant correlation between some exercise ECG variables and angiocardiographic scores used to evaluate the extent and type of coronary heart disease (CHD). In the present study we examined the effects of digitalis, beta-adrenergic blockers, slow release nitrates, calcium channel blockers, presence of arterial hypertension (AHT), and angiocardiographic changes on the exercise ECG variables. The effects of drugs and AHT were small as compared to the effects of the angiocardiographically detected pathological changes caused by the CHD. Sensitivity and specificity of the exercise ECG ST criteria in identifying patients with an angiocardiographic criterion indicating coronary insufficiency were not much different in the whole group and in the subsets with AHT or medication with digitalis and anti-anginal drugs.
我们之前已经发现，某些运动心电图变量与用于评估冠心病（CHD）程度和类型的心血管造影评分之间存在统计学上的显著相关性。在本研究中，我们研究了洋地黄、β-肾上腺素能阻滞剂、缓释硝酸盐、钙通道阻滞剂、动脉高血压（AHT）的存在以及心血管造影变化对运动心电图变量的影响。与冠心病引起的心血管造影检测到的病理变化的影响相比，药物和AHT的影响较小。在整个组以及患有AHT或使用洋地黄和抗心绞痛药物的亚组中，运动心电图ST标准在识别具有心血管造影标准表明冠状动脉供血不足的患者时的敏感性和特异性没有太大差异。
