Lassus A
Curr Med Res Opin. 1976;4(5):365-7. doi: 10.1185/03007997609109330.
A double-blind evaluation was carried out in 40 patients with moderate to severe psoriasis of the scalp to assess the effectiveness of a 0.05% alcoholic solution of clobetasol propionate as compared with a 0.05% alcoholic solution of betamethasone-17,21-dipropionate. Patients were treated on a non-selective basis with a twice a day application for 2 weeks. When comparing the effects on the parameters scaling, induration, erythema and itching it was concluded that clobetasol propionate was superior to betamethasone-17,21-dipropionate as an antipsoriatic compound. Clobetasol propionate did not cause any side-effects, while 2 of the patients using betamethasone-17,21-dipropionate developed a forehead folliculitis during the second week of treatment.
对40例中度至重度头皮银屑病患者进行了双盲评估，以评估0.05%丙酸氯倍他索醇溶液与0.05%倍他米松-17,21-二丙酸酯醇溶液相比的有效性。患者在非选择性基础上接受治疗，每天涂抹两次，持续2周。在比较对鳞屑、硬结、红斑和瘙痒等参数的影响时，得出结论：作为抗银屑病化合物，丙酸氯倍他索优于倍他米松-17,21-二丙酸酯。丙酸氯倍他索未引起任何副作用，而使用倍他米松-17,21-二丙酸酯的2例患者在治疗的第二周出现了前额毛囊炎。
