Vamvakopoulos N C, Modi W S, Floros J
Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda MD.
Cytogenet Cell Genet. 1995;68(1-2):8-10. doi: 10.1159/000133878.
Pulmonary surfactant, a lipoprotein complex is essential for normal lung function. The non-serum surfactant-associated proteins, SP-A, SP-B, and SP-C, play important roles in the biology of pulmonary surfactant. We have mapped the human SP-B gene (SFTP3) to chromosome 2, band 2p12-->p11.2 by fluorescent in situ hybridization.
肺表面活性物质是一种脂蛋白复合物,对正常肺功能至关重要。非血清表面活性物质相关蛋白SP-A、SP-B和SP-C在肺表面活性物质生物学中发挥重要作用。我们通过荧光原位杂交将人类SP-B基因(SFTP3)定位到2号染色体,2p12→p11.2带。