Gu H, Rong L, Sha J Y
Changhai Hospital, Second Military Medical University.
Zhonghua Fu Chan Ke Za Zhi. 1994 May;29(5):268-70, 316.
Serial measurements of plasma oxytocin concentration were done by radioimmunoassay in 38 cases of pregnancy induced hypertension (PIH) and 38 cases of normal pregnancy (NP). The results showed that there was no obvious difference in the plasma oxytocin concentration between patients with early PIH and NP, but a higher concentration in cases with PIH at term pregnancy than that in NP and a significantly higher level in intrapartum women with PIH. The results also indicated a much higher oxytocin concentration in cases of moderate and severe PIH as compared to that of NP. An obviously higher level of plasma oxytocin was found in severe PIH than in mild PIH. Based on this study we suggest that the clinical use of oxytocin in cases with PIH should be different from that in NP.
采用放射免疫分析法对38例妊娠高血压综合征（PIH）患者和38例正常妊娠（NP）孕妇进行了血浆催产素浓度的系列测定。结果显示，早发型PIH患者与NP孕妇的血浆催产素浓度无明显差异，但足月妊娠PIH患者的血浆催产素浓度高于NP孕妇，且PIH产妇在分娩期的血浆催产素水平显著更高。结果还表明，中重度PIH患者的催产素浓度比NP孕妇高得多。重度PIH患者的血浆催产素水平明显高于轻度PIH患者。基于本研究，我们建议PIH患者催产素的临床应用应与NP孕妇有所不同。
