Sievert H, Ensslen R, Merle H, Milde H, Scherer D, Schulze R, Spies H, Utech A
Abteilung Kardiologie und Angiologie, Krankenhaus Bethanien, Frankfurt.
Dtsch Med Wochenschr. 1994 Oct 28;119(43):1458-61. doi: 10.1055/s-2008-1058859.
Between August 1991 and December 1993, a total of 7011 percutaneous transluminal coronary angioplasties (PTCA) were performed. In 24 of them, the acute results were unsatisfactory, an autoperfusion balloon catheter was tolerated without complications and prolonged inflation (30 min to one hour) brought no improvement. In these 24 patients (22 men, two women; mean age 60 [33-81] years) the duration of inflation was, if possible, increased to at least 6 hours. In three patients the inflation had to be terminated after 2 or 4 hours, respectively, because of angina or for technical reasons. In 18 of the 24 patients subsequent angiography demonstrated residual restenosis of less than 50%, with a mean degree of stenosis of 18 +/- 14%. But lasting dilatation was not achieved in 6 patients: occlusion persisted in one and marked residual stenosis in two patients, while stent implantation was required in three. These results indicate that, in case of dissection or acute occlusion with failure after prolonged balloon inflation of 30 to 60 min, extending the duration of inflation to many hours can often produce good results so that stent implantation can be avoided.
1991年8月至1993年12月期间,共进行了7011例经皮腔内冠状动脉成形术(PTCA)。其中24例的急性结果不理想,使用自动灌注球囊导管未出现并发症,延长充气时间(30分钟至1小时)也未带来改善。在这24例患者(22例男性,2例女性;平均年龄60[33 - 81]岁)中,若可能,将充气时间延长至至少6小时。3例患者分别因心绞痛或技术原因在2小时或4小时后不得不终止充气。24例患者中有18例随后的血管造影显示残余再狭窄小于50%,平均狭窄程度为18±14%。但6例患者未实现持久扩张:1例持续闭塞,2例有明显残余狭窄,3例需要植入支架。这些结果表明,在出现夹层或急性闭塞且30至60分钟长时间球囊充气失败的情况下,将充气时间延长至数小时通常可产生良好效果,从而避免植入支架。