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用于评估神经元性过度兴奋综合征的缺血-呼吸增强试验。

The ischaemia-hyperpnea test in the evaluation of neuronal hyperexcitability syndrome.

作者信息

Ronchi O, Lolli F, Lori S, Nuti Ranucci E, Grippo A

机构信息

Dipartimento di Scienze Neurologiche e Psichiatriche, Università di Firenze.

出版信息

Electromyogr Clin Neurophysiol. 1994 Jul-Aug;34(5):289-94.

PMID:7956879
Abstract

Electromyography (EMG) identifies abnormalities in the neuronal hyperexcitability syndrome (NHS) with high frequencies of false positive results. We examined 25 subjects with autonomic, psychic and neuromuscular symptoms of NHS. They underwent the ischaemia-hyperpnea test using stringent time criteria to study their symptoms as well as their electrolytical balance. The Kaplan-Meier analysis showed a significantly different incidence of repetitive discharges in the two groups in the post-ischaemic period (p < 0.004) and during hyperpnea (p < 0.001). The ischaemia-hyperpnea EMG test, when evaluated in relation to the the duration of activation procedure, was able to differentiate NHS patients from controls only within 4-6 minutes of ischaemia or hyperpnea. When restricted to this period, EMG observation with the triggering of Ischaemia-hyperpnea identified NHS with a high degree of sensitivity and specificity.

摘要

肌电图(EMG)可识别神经元性兴奋性增高综合征(NHS)中的异常情况,但假阳性结果的频率较高。我们检查了25名有NHS自主神经、精神和神经肌肉症状的受试者。他们接受了缺血-深呼吸试验,采用严格的时间标准来研究其症状以及电解质平衡。Kaplan-Meier分析显示,两组在缺血后阶段(p < 0.004)和深呼吸期间(p < 0.001)重复放电的发生率有显著差异。当根据激活程序的持续时间进行评估时,缺血-深呼吸肌电图测试仅在缺血或深呼吸4 - 6分钟内能够区分NHS患者与对照组。当限于此时间段时,通过触发缺血-深呼吸进行的肌电图观察能够以高度的敏感性和特异性识别NHS。

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