Caufriez A, Frankenne F, Hennen G, Copinschi G
Department of Obstetrics and Gynaecology, Université Libre de Bruxelles, Belgium.
Horm Res. 1994;42(1-2):62-5. doi: 10.1159/000184147.
In normal and in pathological human pregnancies, a specific placental growth hormone variant, rather than placental lactogen, substitutes for the suppressed pituitary GH to stimulate the maternal insulin-like growth factor I (IGF-I). In pathological pregnancies with disorders of the feto-placental unit, low levels of placental GH hormone result in relatively low levels of maternal IGF-I. In normal pregnancies, the baby birth weight is positively correlated with maternal IGF-I values.
在正常和病理性人类妊娠中，一种特定的胎盘生长激素变体而非胎盘催乳素，替代受抑制的垂体生长激素来刺激母体胰岛素样生长因子I（IGF-I）。在胎儿-胎盘单位出现紊乱的病理性妊娠中，胎盘生长激素水平低会导致母体IGF-I水平相对较低。在正常妊娠中，婴儿出生体重与母体IGF-I值呈正相关。
