Mattei M G, Giannini G, Moscatelli F, Sorrentino V
Unité INSERM 242, Hôpital d'Enfants de la Timone, Marseille, France.
Genomics. 1994 Jul 1;22(1):202-4. doi: 10.1006/geno.1994.1362.
In situ hybridization experiments were performed using complementary DNA probes to determine the location on murine chromosomes of the three genes of the ryanodine receptor/Ca2+ channel family: RYR1, RYR2, and RYR3. The skeletal ryanodine receptor, or type 1 (Ryr1), maps to bands 7A2-7A3; the cardiac ryanodine receptor, or type 2 (Ryr2), to 13A1-13A2; and type 3 (Ryr3) to 2E5-2F3.
使用互补DNA探针进行原位杂交实验,以确定兰尼碱受体/Ca2+通道家族的三个基因(RYR1、RYR2和RYR3)在小鼠染色体上的位置。骨骼肌兰尼碱受体,即1型(Ryr1),定位于7A2 - 7A3带;心脏兰尼碱受体,即2型(Ryr2),定位于13A1 - 13A2带;3型(Ryr3)定位于2E5 - 2F3带。