睾酮对去势大鼠抗坏血酸代谢的长期给药研究。
Long term administration of testosterone on ascorbic acid metabolism in castrated rats.
作者信息
Kumari K T, Menon V P, Leelamma S
机构信息
Department of Biochemistry, University of Kerala Kariavattom, Trivandrum, India.
出版信息
Indian J Exp Biol. 1994 Jul;32(7):458-60.
PMID:7959920
Abstract
Orchidectomy caused a significant decrease in the concentration of ascorbic acid and ascorbic acid-2-sulphate in tissues while administration of testosterone to these animals reverses this effect. Concentration of ascorbic acid in liver in experimental groups correlates with the activity of L-qualano-lactone oxidase and dehydroascorbatase in this tissue.
摘要
睾丸切除术导致组织中抗坏血酸和抗坏血酸-2-硫酸盐的浓度显著降低，而给这些动物注射睾酮可逆转这种效应。实验组肝脏中抗坏血酸的浓度与该组织中L-奎诺内酯氧化酶和脱氢抗坏血酸酶的活性相关。
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