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[丘疹性黏蛋白病。红斑狼疮一种罕见的皮肤表现]

[Papular mucinosis. A rare cutaneous manifestation of lupus erythematosus].

作者信息

Storck R, Schirren C G, Meurer M, Kind P

机构信息

Dermatologische Klinik und Poliklinik, Ludwig-Maximilians-Universität, München.

出版信息

Hautarzt. 1994 Sep;45(9):642-6. doi: 10.1007/s001050050143.

Abstract

The case of a 48-year-old patient with systemic lupus erythematosus is discussed. Under immunosuppressive therapy, symptomless papules occurred on the shoulders, back, chest and face. Histologically, there were deposits of mucinous matter which produced an intensive blue colour in the HALE-PAS and alcian blue colour test. The epidermal and dermal inflammatory changes which typically occur with lupus erythematosus were absent. Whereas mucin is commonly diagnosed in lupus erythematosus, the clinical manifestation of papulous mucinosis is a rare but diagnostically significant phenomenon, since it can occur without further findings which are typical of lupus erythematosus.

摘要

讨论了一名48岁系统性红斑狼疮患者的病例。在免疫抑制治疗期间,患者肩部、背部、胸部和面部出现无症状丘疹。组织学检查显示,有黏液物质沉积,在HALE-PAS染色和阿尔辛蓝染色试验中呈深蓝色。狼疮红斑通常出现的表皮和真皮炎症改变并不存在。虽然黏液在红斑狼疮中常见,但丘疹性黏液水肿的临床表现是一种罕见但具有诊断意义的现象,因为它可以在没有红斑狼疮典型的其他表现的情况下出现。

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