Min H, Hong M, Ma J, Zhang E, Zheng Q, Zhang J, Zhang J, Zhang F, Su Y, Qiu F
Department of NPC, Sun Yat-sen University of Medical Sciences, Guangzhou, P.R. China.
Int J Radiat Oncol Biol Phys. 1994 Dec 1;30(5):1037-42.
An accurate and rational nasopharyngeal carcinoma (NPC) stage based on images is proposed.
Four hundred and twenty-one cases of NPC, treated in the Cancer Hospital, Sun Yat-sen University of Medical Sciences (SUMS), with computed tomography scanning before initial radiotherapy, are analyzed. Important prognostic factors that form the basis of the new staging system are screened out by means of Cox model and clinical experiences. Survival curves of various kinds of T and N stages are compared by computer simulation. A new staging system is proposed by studying the traditional staging systems such as the AJC, UICC, Ho's and Changsha systems.
According to the new staging criteria, the 5-year survival rates for Stages I-IV are 89.7%, 75.9%, 51.3%, and 22.2%, respectively.
This new clinical staging for NPC based on a large amount of cases multivariate analysis is satisfactory and widely used in China.
提出一种基于影像的准确且合理的鼻咽癌（NPC）分期。
分析了421例在中山医科大学肿瘤医院接受治疗的鼻咽癌患者，这些患者在初次放疗前均进行了计算机断层扫描。通过Cox模型和临床经验筛选出构成新分期系统基础的重要预后因素。通过计算机模拟比较了各种T和N分期的生存曲线。通过研究如AJC、UICC、Ho氏和长沙分期系统等传统分期系统，提出了一种新的分期系统。
根据新的分期标准，I - IV期的5年生存率分别为89.7%、75.9%、51.3%和22.2%。
这种基于大量病例多因素分析的鼻咽癌新临床分期令人满意，在中国得到广泛应用。
