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Bioequivalence of two oral dosage forms prepared from different polymorphic modifications of tenoxicam.

作者信息

Salem M S, Alkaysi H N, Gharaibeh A M, Gharaibeh N M, Badwan A A

机构信息

Faculty of Pharmacy, University of Science and Technology, Irbid, Jordan.

出版信息

J Clin Pharm Ther. 1994 Jun;19(3):203-7. doi: 10.1111/j.1365-2710.1994.tb00674.x.

DOI:10.1111/j.1365-2710.1994.tb00674.x
PMID:7962225
Abstract

The bioavailability of two pharmaceutical dosage forms formulated using different polymorphs of tenoxicam were compared. Serum levels of TNX were analysed using high performance liquid chromatography. The pharmacokinetic parameters were estimated following the oral administration of a single dose (20 mg) of the drug as two different polymorphs to 12 healthy volunteers. The differences between formulations were statistically insignificant.

摘要

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