Ormiston I W, Piette E, Tideman H, Wu P C
Department of Oral and Maxillofacial Surgery, University of Hong Kong.
J Craniomaxillofac Surg. 1994 Aug;22(4):231-5. doi: 10.1016/s1010-5182(05)80563-3.
A review of the literature and the addition of 2 cases in the mandibular symphyseal region serve to illustrate the protean presentation of chondrosarcomas. These 2 cases presented as periodontal lesions with associated bone loss. A high index of suspicion is required to make an early diagnosis. The importance of submitting biopsy specimens for histology is stressed, and it is recommended that definitive treatment be carried out as rapidly as possible after diagnosis is known. The surgical procedures undertaken were conservative, and patients have remained disease-free after 3.5 years and 3 years respectively. For small lesions, early segmental resection is not necessary in this region. Only recurrence should be treated by symphyseal resection with its increased morbidity. Close follow-up is mandatory.
对文献的回顾以及下颌骨联合区的2例病例补充，有助于说明软骨肉瘤的多种表现形式。这2例表现为伴有相关骨质流失的牙周病变。早期诊断需要高度的怀疑指数。强调提交活检标本进行组织学检查的重要性，建议在确诊后尽快进行确定性治疗。所采取的手术操作较为保守，患者分别在3.5年和3年后仍无疾病复发。对于该区域的小病变，早期节段性切除并非必要。只有复发时才应进行联合切除术，但该手术发病率较高。密切随访是必需的。
