Drummond D C, Glautier S
Addiction Research Unit, National Addiction Centre, Institute of Psychiatry, London, United Kingdom.
J Consult Clin Psychol. 1994 Aug;62(4):809-17. doi: 10.1037//0022-006x.62.4.809.
The clinical effectiveness of cue exposure (CE) treatment in alcohol dependence was evaluated in a controlled trial. Thirty-five men who were detoxified and severely alcohol dependent received either CE or relaxation control (RC) treatment. CE Ss had 400 min exposure to the sight and smell of preferred drinks over 10 days in a laboratory setting. RC Ss spent identical time in the laboratory but had relaxation therapy and only 20 min exposure to alcohol cues. During 6-month follow-up, personal interview was achieved with 91% of Ss. CE Ss had a more favorable outcome than the RC Ss in terms of latency (length of time) to relapse of heavy drinking (p < .01) and total alcohol consumption (p < .05). Significant predictors of latency to heavy drinking and dependence included skin conductance level (p < .001) and experimental condition (p < .01). Results point to the potential importance of cue exposure as a treatment for addictive behavior.
在一项对照试验中评估了线索暴露（CE）疗法对酒精依赖的临床疗效。35名已戒酒且严重酒精依赖的男性接受了CE或放松控制（RC）治疗。CE组的受试者在实验室环境中，在10天内接触了400分钟偏好饮料的视觉和嗅觉。RC组的受试者在实验室里度过相同的时间，但接受了放松疗法，且仅接触20分钟的酒精线索。在6个月的随访期间，91%的受试者接受了个人访谈。在重度饮酒复发的潜伏期（时间长度）（p < .01）和总酒精摄入量方面（p < .05），CE组的受试者比RC组有更有利的结果。重度饮酒和依赖潜伏期的显著预测因素包括皮肤电导率水平（p < .001）和实验条件（p < .01）。结果表明线索暴露作为一种成瘾行为治疗方法具有潜在的重要性。
