Yamamoto T, Ohkubo H, Katayama I, Nishioka K
Department of Dermatology, Tokyo Metropolitan Bokuto Hospital, Japan.
J Dermatol. 1994 Sep;21(9):687-9. doi: 10.1111/j.1346-8138.1994.tb01818.x.
A 63-year-old woman with dermatomyositis (DM) developed multiple punched-out ulcers of the skin. She had not only a past history of gastric cancer 10 years prior to the onset of DM, but also a familial history of cancer. A skin biopsy from one of the ulcers revealed both vasculitis and membrano-cystic lesion in the same specimen. She died of interstitial pneumonitis one year after the onset of DM. Vasculitis and membrano-cystic lesion may be an important marker of a poor prognosis in DM.
一名63岁的皮肌炎(DM)女性患者出现了多处皮肤穿凿性溃疡。她不仅在DM发病前10年有胃癌病史,而且有癌症家族史。对其中一个溃疡进行的皮肤活检显示,同一样本中既有血管炎又有膜性囊肿病变。DM发病一年后,她死于间质性肺炎。血管炎和膜性囊肿病变可能是DM预后不良的重要标志。