Straub R F, Wilcox C M, Schwartz D A
Department of Medicine, Emory University School of Medicine, Atlanta, Georgia.
J Clin Gastroenterol. 1994 Sep;19(2):158-64; discussion 164-5. doi: 10.1097/00004836-199409000-00018.
The variable appearance of gut-associated lymphoid tissue at videocolonoscopy has not been well documented. Over a 3-year period all patients undergoing high resolution videcolonoscopy underwent biopsy of any identified abnormalities for correlating histopathologic findings with endoscopic appearance. We identified several distinct patterns for lymphoid tissue: small well-circumscribed nodules, red rings, large coalescing vesicles with or without central pits, or white plaques. A mass-like appearance of the ileocecal valve was present in one patient. Although individually each of these patterns appeared characteristic, overall, variability appeared dependent on the colonic location and underlying disease. Prominent lymphoid tissue was most frequently seen in patients with underlying disorders resulting in stimulation of the immune system. We take this to mean that there is a broader spectrum of colonic lymphoid tissue as assessed by videocolonoscopy than previously appreciated. The variability of these normal structures has potential diagnostic implications.
在电子结肠镜检查中，肠道相关淋巴组织的可变外观尚未得到充分记录。在3年的时间里，所有接受高分辨率电子结肠镜检查的患者，对任何发现的异常情况都进行了活检，以将组织病理学结果与内镜表现相关联。我们确定了淋巴组织的几种不同模式：边界清晰的小结节、红色环、有或无中央凹陷的大融合性水疱或白色斑块。一名患者的回盲瓣出现肿块样外观。虽然这些模式中的每一种单独看起来都具有特征性，但总体而言，变异性似乎取决于结肠位置和潜在疾病。在导致免疫系统受刺激的潜在疾病患者中，最常出现明显的淋巴组织。我们认为，通过电子结肠镜检查评估的结肠淋巴组织范围比以前认识的更广。这些正常结构的变异性具有潜在的诊断意义。
