Sottiurai V S, Jones R, Nakamura Y A, Boustany C, Sue S L, Batson R C
Louisiana State University Medical Center, School of Medicine in New Orleans, LA.
Int Angiol. 1994 Jun;13(2):96-102.
Comparison of the cumulative patency of four types of Polytetrafluoroethylene (PTFE) grafts with and without a vein patch at the distal anastomosis in one hundred and twenty ilio-femoral by-passes of sixty dogs revealed: (i) Vein patch improved patency in standard PTFE graft 10/16 (62.5%) versus without a vein patch 6/16 (27.5%) (p < 0.1). (ii) The less rigid thin wall PTFE graft did not benefit from vein patching 22/45 (48.8%) versus those without a vein patch 28/45 (62.2%) (p < 0.2). (iii) DAIH was present in all grafts with and without a vein patch and occurred exclusively at the heel and the toe of the graft plus the floor of the host artery three months after implantation. (iv) An organized fibrocellular multilamination characterized the cytoarchitecture of the DAIH. (v) A process of gradual cell transformation and orientation occurred in DAIH that spanned between the graft and the lumen. Vein patch at the distal anastomosis improved the patency of the more rigid standard PTFE grafts, and adversely affected the less rigid thin walled PTFE graft in dogs. The formation and distribution of DAIH was not altered by a vein patch at the distal anastomosis of PTFE grafts.
在60只犬的120例髂股旁路手术中，比较了四种聚四氟乙烯（PTFE）移植物在远端吻合口有无静脉补片时的累积通畅率，结果显示：（i）静脉补片可提高标准PTFE移植物的通畅率，有静脉补片的为10/16（62.5%），无静脉补片的为6/16（27.5%）（p<0.1）。（ii）柔韧性较差的薄壁PTFE移植物未从静脉补片中获益，有静脉补片的为22/45（48.8%），无静脉补片的为28/45（62.2%）（p<0.2）。（iii）植入后三个月，所有有和无静脉补片的移植物中均出现DAIH，且仅发生在移植物的足跟和趾端以及宿主动脉的底部。（iv）DAIH的细胞结构以有组织的纤维细胞多层化为特征。（v）DAIH中发生了一个逐渐的细胞转化和定向过程，跨越移植物和管腔。远端吻合口的静脉补片改善了柔韧性较强的标准PTFE移植物的通畅率，但对犬体内柔韧性较差的薄壁PTFE移植物有不利影响。PTFE移植物远端吻合口的静脉补片未改变DAIH的形成和分布。
