通过针刺在裸鼠中传播麻风病。
Transmission of leprosy in nude mice through thorn pricks.
作者信息
Job C K, Chehl S K, Hastings R C
机构信息
Laboratory Research Branch, GWL Hansen's Disease Center, Louisiana State University, Baton Rouge 70894.
出版信息
Int J Lepr Other Mycobact Dis. 1994 Sep;62(3):395-8.
The dorsum of the feet of 10 nude mice was smeared with 10(7) Mycobacterium leprae and then pricked with cactus thorns contaminated with M. leprae. In 15 months five of them developed lepromatous nodules at the infected site and disseminated lesions in the ears, nose, tail and the organs of the reticuloendothelial system. Penetrating injuries through unprotected skin contaminated with M. leprae from the environment may play a role in the transmission of leprosy in humans.
在10只裸鼠的足背涂抹10⁷ 麻风分枝杆菌，然后用沾染了麻风分枝杆菌的仙人掌刺进行针刺。15个月内，其中5只在感染部位出现瘤型结节，并在耳朵、鼻子、尾巴和网状内皮系统器官出现播散性病变。通过接触环境中沾染麻风分枝杆菌的未防护皮肤造成的穿透性损伤可能在人类麻风传播中起作用。
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