Schechter D, Bocher M, Berlatzky Y, Anner H, Argov Z, Beer G, Krausz Y, Gotsman M S, Chisin R
Department of Medical Biophysics and Nuclear Medicine, Hadassah University Hospital, Jerusalem, Israel.
J Nucl Med. 1994 Nov;35(11):1802-4.
Dipyridamole-associated adverse neurological side effects have not been extensively described. We present two cases of dipyridamole-associated transient motor neurological events with no evidence of residual neurological deficits detected clinically or by head CT. The patients showed no evidence of significant extracranial (internal carotid) artery disease. We propose the presence of a regional cerebral perfusion disturbance due to an intracranial vascular steal phenomenon as the mechanism for the above side effects of dipyridamole.
双嘧达莫相关的不良神经副作用尚未得到广泛描述。我们报告两例双嘧达莫相关的短暂性运动神经事件,临床及头颅CT均未发现残留神经功能缺损的证据。患者未显示出明显的颅外(颈内动脉)血管疾病迹象。我们提出,颅内血管窃血现象导致的局部脑灌注紊乱是双嘧达莫上述副作用的机制。