Rizzo G, Pietropolli A, Capponi A, Cacciatore C, Arduini D, Romanini C
Department of Obstetrics and Gynecology, University of Rome Tor Vergata, Italy.
J Perinat Med. 1994;22(2):149-57. doi: 10.1515/jpme.1994.22.2.149.
In an effort to determine the factors influencing the abnormal ventricular filling patterns of fetuses of type I diabetic mothers, Doppler flow velocity waveforms were recorded from fetal atrioventricular valves in 37 pregnancies complicated by type I diabetes immediately before an elective cesarean section. The ratio between the peak velocities during early passive ventricular filling and active atrial filling was calculated at the level of both atrioventricular valves and related to different factors including ventricular chamber wall thickness, heart rate, umbilical vein hematocrit and time to peak velocities values obtained at the outflow tract. Multiple stepwise regression demonstrated that the interventricular wall thickness, heart rate and hematocrit values significantly and independently affected the ratios between early and active ventricular filling from mitral and tricuspid valves. As a consequence all these factors should be taken into account in the interpretation of atrioventricular Doppler indices.
为了确定影响I型糖尿病母亲胎儿心室充盈模式异常的因素，在37例合并I型糖尿病的妊娠孕妇行择期剖宫产术前，记录胎儿房室瓣的多普勒流速波形。计算两个房室瓣水平早期被动心室充盈和主动心房充盈期间的峰值速度之比，并与包括心室壁厚度、心率、脐静脉血细胞比容以及流出道获得的峰值速度时间等不同因素相关联。多元逐步回归分析表明，室间隔厚度、心率和血细胞比容值显著且独立地影响二尖瓣和三尖瓣早期与主动心室充盈之间的比值。因此，在解释房室多普勒指标时应考虑所有这些因素。
