Turner B J, Markson L E, McKee L J, Houchens R, Fanning T
Center for Research in Medical Education and Health Care, Thomas Jefferson University, Philadelphia, PA.
J Acquir Immune Defic Syndr (1988). 1994 Dec;7(12):1250-62.
The aim of this study was to define predictors of survival for women and men after AIDS diagnosis. We examined health care delivery and drug therapy in the year before AIDS diagnosis for continuously enrolled New York State Medicaid beneficiaries with AIDS in 1988-1990. We examined the association of these factors with survival after AIDS diagnosis. Of 1,077 women and 1,871 men, 60% of both gender groups were drug users. In both risk groups, women had more outpatient visits than men but were equally likely to visit an AIDS specialist. In those who were not drug users, men were twice as likely as women to receive either zidovudine or Pneumocystis carinii pneumonia prophylaxis. No difference appeared among drug users. Survival after AIDS diagnosis was similar by gender for those who were not drug users (RR = 1.09; 95% CI = 0.90-1.33). In drug users, women had a slightly lower risk of death than men (RR = 0.84; 95% CI = 0.72-0.98). Risk of death after AIDS diagnosis was higher for persons starting zidovudine earlier in both risk groups. Among drug users, women received more ambulatory care and survived slightly longer than men. Among those who were not drug users, survival was similar by gender even after adjusting for differences in care.
本研究的目的是确定艾滋病诊断后女性和男性的生存预测因素。我们调查了1988 - 1990年纽约州医疗补助计划中持续参保的艾滋病患者在艾滋病诊断前一年的医疗服务提供情况和药物治疗情况。我们研究了这些因素与艾滋病诊断后生存情况的关联。在1077名女性和1871名男性中,两个性别组均有60%为吸毒者。在两个风险组中,女性的门诊就诊次数多于男性,但看艾滋病专科医生的可能性相同。在非吸毒者中,男性接受齐多夫定或卡氏肺孢子虫肺炎预防治疗的可能性是女性的两倍。吸毒者之间未发现差异。非吸毒者艾滋病诊断后的生存情况按性别来看相似(相对危险度=1.09;95%可信区间=0.90 - 1.33)。在吸毒者中,女性的死亡风险略低于男性(相对危险度=0.84;95%可信区间=0.72 - 0.98)。在两个风险组中,较早开始使用齐多夫定的人艾滋病诊断后的死亡风险更高。在吸毒者中,女性接受的门诊护理更多,存活时间比男性略长。在非吸毒者中,即使调整了护理差异,按性别来看生存情况仍相似。