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死海地区银屑病关节炎的治疗。

Treatment of psoriatic arthritis at the Dead Sea.

作者信息

Sukenik S, Giryes H, Halevy S, Neumann L, Flusser D, Buskila D

机构信息

Department of Medicine D, Epidemiology, Soroka Medical Center of Kupat-Holim, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.

出版信息

J Rheumatol. 1994 Jul;21(7):1305-9.

PMID:7966074
Abstract

OBJECTIVE

To evaluate the effectiveness of balneotherapy (mud packs and sulfur baths) on patients with psoriasis and psoriatic arthritis (PsA).

METHODS

One hundred and sixty-six patients with psoriasis and PsA were treated at the Dead Sea for a period of 3 weeks. The patients were divided into 2 groups. Both groups had the regular regimen of bathing in Dead Sea water and exposure to the sun's ultraviolet rays. The study group, which consisted of 146 patients also was treated with mud packs and sulfur baths. The control group, which had no additional therapy, consisted of 20 patients. The main clinical variables assessed were duration of morning stiffness, grip strength, activities of daily living, subjective patient assessment of disease severity, number of active joints, number of effluent joints. Ritchie index, psoriasis area and severity index score, cervical, thoracic, and lumbar spine pain and limitations of movement.

RESULTS

Statistically significant improvement was found in most variables in both groups. However, better results were observed in the study group. In 2 variables, reduction of spinal pain and range of movement in the lumbar spine, significant improvement (p < 0.001 and p = 0.022, respectively) was observed in the study group only.

CONCLUSION

Treatment of psoriasis and PsA at the Dead Sea area is very efficacious and the addition of balneotherapy can have additional beneficial effects on patients with PsA. Other controlled studies with longer followup periods are needed to verify our results.

摘要

目的

评估温泉疗法(泥疗和硫磺浴)对银屑病和银屑病关节炎(PsA)患者的疗效。

方法

166例银屑病和PsA患者在死海接受了为期3周的治疗。患者被分为两组。两组均采用在死海海水中沐浴并接受太阳紫外线照射的常规方案。研究组由146例患者组成,还接受了泥疗和硫磺浴。对照组由20例患者组成,未接受额外治疗。评估的主要临床变量包括晨僵持续时间、握力、日常生活活动能力、患者对疾病严重程度的主观评估、活动关节数、渗出关节数、里奇指数、银屑病面积和严重程度指数评分、颈椎、胸椎和腰椎疼痛及活动受限情况。

结果

两组中大多数变量均有统计学意义的改善。然而,研究组的结果更好。在两个变量中,即腰椎疼痛减轻和腰椎活动范围,仅在研究组中观察到显著改善(分别为p < 0.001和p = 0.022)。

结论

在死海地区治疗银屑病和PsA非常有效,温泉疗法的加入对PsA患者可能有额外的有益效果。需要其他随访期更长的对照研究来验证我们的结果。

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