• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Comparison of the ToxA test with cytotoxicity assay and culture for the detection of Clostridium difficile-associated diarrhoea disease.

作者信息

Schué V, Green G A, Monteil H

机构信息

Laboratoire de Toxinologie Bactérienne, Faculté de Médecine, Université Louis-Pasteur Strasbourg, France.

出版信息

J Med Microbiol. 1994 Nov;41(5):316-8. doi: 10.1099/00222615-41-5-316.

DOI:10.1099/00222615-41-5-316
PMID:7966202
Abstract

Stool samples (355 from 350 patients) were examined in a new commercial assay, the ToxA test, for the rapid diagnosis of Clostridium difficile-associated diarrhoea. The results were compared with direct assay of cytotoxin in McCoy cell tissue culture, and detection of toxigenic C. difficile by culture and cytotoxin testing of isolates. Discordant results were resolved by consultation of clinical records. Test sensitivities were 84.6% for the ToxA test, 78.5% for the direct cytotoxicity assay and 95.4% for culture. The specificity was 100% for all the tests. The ToxA test is a rapid and reliable alternative for the detection of toxigenic C. difficile where tissue culture facilities are unavailable.

摘要

相似文献

1
Comparison of the ToxA test with cytotoxicity assay and culture for the detection of Clostridium difficile-associated diarrhoea disease.
J Med Microbiol. 1994 Nov;41(5):316-8. doi: 10.1099/00222615-41-5-316.
2
Clostridium difficile and its cytotoxin in diarrhoeic stools of hospitalized patients. Toxigenic potential of the isolates.住院患者腹泻粪便中的艰难梭菌及其细胞毒素。分离株的产毒潜力。
Ann Biol Clin (Paris). 1989;47(2):67-70.
3
Laboratory diagnosis of Clostridium difficile-associated diarrhea and colitis: usefulness of Premier Cytoclone A+B enzyme immunoassay for combined detection of stool toxins and toxigenic C. difficile strains.艰难梭菌相关性腹泻和结肠炎的实验室诊断：Premier Cytoclone A+B酶免疫测定法联合检测粪便毒素和产毒艰难梭菌菌株的实用性
J Clin Microbiol. 2001 May;39(5):1996-8. doi: 10.1128/JCM.39.5.1996-1998.2001.
4
Evaluation of biosite triage Clostridium difficile panel for rapid detection of Clostridium difficile in stool samples.用于粪便样本中艰难梭菌快速检测的生物位点分诊艰难梭菌检测板评估。
J Clin Microbiol. 2001 May;39(5):1855-8. doi: 10.1128/JCM.39.5.1855-1858.2001.
5
Evaluation of different methods for detection of Clostridium difficile toxins in Poland.波兰不同艰难梭菌毒素检测方法的评估。
Acta Microbiol Pol. 1999;48(4):349-53.
6
[Investigation of toxin genes of Clostridium difficile strains isolated from hospitalized patients with diarrhoea at Marmara University Hospital].[对从马尔马拉大学医院腹泻住院患者中分离出的艰难梭菌菌株毒素基因的研究]
Mikrobiyol Bul. 2011 Jan;45(1):1-10.
7
Diagnosing toxigenic Clostridium difficile: new confidence bounds show culturing increases sensitivity of the toxin A/B enzyme immunoassay and refute gold standards.诊断产毒艰难梭菌：新的置信区间表明培养可提高毒素A/B酶免疫测定的灵敏度并反驳金标准。
Scand J Infect Dis. 2012 Aug;44(8):578-85. doi: 10.3109/00365548.2012.655772. Epub 2012 Mar 11.
8
Importance of culture for detection of Clostridium difficile toxin from stool samples to report true incidence and mortality related to C. difficile in hospitals.培养对于从粪便样本中检测艰难梭菌毒素以报告医院中与艰难梭菌相关的真实发病率和死亡率的重要性。
Clin Infect Dis. 2009 Oct 1;49(7):1134-5; author reply 1135. doi: 10.1086/605596.
9
Evaluation of five enzyme immunoassays compared with the cytotoxicity assay for diagnosis of Clostridium difficile-associated diarrhea in dogs.五种酶免疫测定法与细胞毒性测定法用于诊断犬艰难梭菌相关性腹泻的比较评估。
J Vet Diagn Invest. 2006 Mar;18(2):182-8. doi: 10.1177/104063870601800207.
10
Performance of the TechLab C. DIFF CHEK-60 enzyme immunoassay (EIA) in combination with the C. difficile Tox A/B II EIA kit, the Triage C. difficile panel immunoassay, and a cytotoxin assay for diagnosis of Clostridium difficile-associated diarrhea.TechLab艰难梭菌检测-60酶免疫测定法（EIA）联合艰难梭菌毒素A/B II EIA试剂盒、Triage艰难梭菌检测板免疫测定法及细胞毒素测定法用于诊断艰难梭菌相关性腹泻的性能
J Clin Microbiol. 2004 Oct;42(10):4863-5. doi: 10.1128/JCM.42.10.4863-4865.2004.

引用本文的文献

1
Development of an ELISA kit using monoclonal antibody to Clostridium difficile toxin A.使用抗艰难梭菌毒素A单克隆抗体开发酶联免疫吸附测定试剂盒。
World J Gastroenterol. 2004 Sep 15;10(18):2747-9. doi: 10.3748/wjg.v10.i18.2747.
2
Evaluation of a new enzyme immunoassay for Clostridium difficile toxin A.艰难梭菌毒素A新型酶免疫测定法的评估
J Clin Pathol. 1997 Dec;50(12):996-1000. doi: 10.1136/jcp.50.12.996.