Tomita A
Department of Laboratory Medicine, Aichi Medical University.
Nihon Rinsho. 1994 Sep;52(9):2415-9.
Secondary osteoporosis may be associated with a number of endocrine dysfunctions and metabolic disorders. In this paper, osteoporosis in patients with Cushing's syndrome, hyperthyroidism, primary hyperparathyroidism, acromegaly, hypogonadism and some metabolic disorders such as diabetes mellitus, chronic renal failure and malabsorption syndrome are described. While the major manifestation of bone in these conditions is a reduction of bone mass and may be somewhat different from bone loss in primary osteoporosis histologically or radiologically, it is considered to be the same bone loss as primary osteoporosis in the present paper. In some conditions, for example, Cushing's syndrome, diabetes mellitus etc, factors responsible for bone loss are demonstrated.
继发性骨质疏松可能与多种内分泌功能障碍和代谢紊乱有关。本文描述了库欣综合征、甲状腺功能亢进症、原发性甲状旁腺功能亢进症、肢端肥大症、性腺功能减退症患者的骨质疏松以及一些代谢紊乱,如糖尿病、慢性肾衰竭和吸收不良综合征。虽然在这些情况下骨骼的主要表现是骨量减少,在组织学或放射学上可能与原发性骨质疏松症的骨质流失有所不同,但在本文中仍被认为与原发性骨质疏松症的骨质流失相同。在某些情况下,例如库欣综合征、糖尿病等,已经证实了导致骨质流失的因素。