Fujita J, Negayama K, Xu G, Hojo S, Takigawa K, Yamagishi Y, Miyawaki H, Fujita T, Yamaji Y, Okada H
First Department of Internal Medicine, Kagawa Medical School.
Nihon Kyobu Shikkan Gakkai Zasshi. 1994 Jul;32(7):638-43.
Between January 1988 and December 1992, 68 patients admitted to our Department of Internal Medicine with hematological malignancies or solid tumors showed colonization of the respiratory tract with Xanthomonas maltophilia (X. maltophilia). To characterize the significance of respiratory tract colonization by X. maltophilia, we retrospectively reviewed the medical records of the 68 patients colonized with this organism. Twenty-seven of these 68 patients developed pneumonia, with X. maltophilia being implicated in 10 cases. The majority of the 10 patients showed lobular infiltration on chest X-ray. Pleural effusion was observed in 2 (20%) of the 10 patients. All 68 strains of X. maltophilia were resistant to imipenem/cilastatin. Most strains (98.5%) were sensitive to latamoxef, while all strains were sensitive to minocycline. This report describes the clinical features of nosocomial X. maltophilia pneumonia in immunocompromised patients.
1988年1月至1992年12月期间，我院内科收治的68例血液系统恶性肿瘤或实体瘤患者出现嗜麦芽窄食单胞菌呼吸道定植。为了明确嗜麦芽窄食单胞菌呼吸道定植的意义，我们回顾性分析了这68例该菌定植患者的病历。这68例患者中有27例发生肺炎，其中10例与嗜麦芽窄食单胞菌有关。这10例患者中的大多数胸部X线表现为小叶性浸润。10例患者中有2例（20%）出现胸腔积液。所有68株嗜麦芽窄食单胞菌对亚胺培南/西司他丁耐药。大多数菌株（98.5%）对拉氧头孢敏感，而所有菌株对米诺环素敏感。本报告描述了免疫功能低下患者医院内嗜麦芽窄食单胞菌肺炎的临床特征。
