Nakagawa H, Namima T, Aizawa M, Uchi K, Orikasa S
Department of Urology, Tohoku University School of Medicine, Sendai, Japan.
Nihon Hinyokika Gakkai Zasshi. 1994 Sep;85(9):1399-402. doi: 10.5980/jpnjurol1989.85.1399.
We reported three cases of neurogenic bladder due to neuro-Beçhet disease. Case 1 (24-year-old male) and case 3 (54-year-old male) had complaint of urinary frequency and urinary incontinence. Case 2 (35-year-old male) had a complaint of urinary retention. Uro-dynamic study were performed repeatedly in each case. Two cases showed overative detrusor activity in storage phase and normal or hypo detrusor activity in voiding phase. One case (case 2) showed normal detrusor activity in storage phase and acontractile in voiding phase. All cases showed detrusor-sphincter dyssynergia (DSD). All cases were managed with clean intermittent catheterization. Six months later case 2 complained of urge incontinence. Repeated uro-dynamic study revealed that bladder function changed from normal detrusor to overactive detrusor in storage phase. These findings suggest that neurogenic bladder due to neuro-Beçhet disease is characterized uro-dynamical by overactive detrusor in storage phase and DSD in voiding phase.
我们报告了3例神经白塞病所致神经源性膀胱病例。病例1（24岁男性）和病例3（54岁男性）主诉尿频和尿失禁。病例2（35岁男性）主诉尿潴留。对每个病例均反复进行了尿动力学研究。2例在储尿期表现为逼尿肌过度活动，排尿期表现为正常或逼尿肌活动减弱。1例（病例2）储尿期逼尿肌活动正常，排尿期无收缩。所有病例均表现为逼尿肌-括约肌协同失调（DSD）。所有病例均采用清洁间歇性导尿治疗。6个月后，病例2主诉急迫性尿失禁。重复尿动力学研究显示，膀胱功能在储尿期从正常逼尿肌转变为逼尿肌过度活动。这些发现表明，神经白塞病所致神经源性膀胱的尿动力学特征为储尿期逼尿肌过度活动和排尿期DSD。
