Kostko S Z
Kardiologiia. 1993;33(5):55-7.
Electromagnetic flowmetry and analogue computers were used to evaluate changes in great venous and arterial blood flow and resistance alterations in the vessels after nifedipine and verapamil in experiments with 12 anesthesized cats. The agents were demonstrated to increase cardiac output due to lower afterload and venous return, to redistribute cardiac output towards greater brain blood supply. The latter was caused by a more marked decrease in vascular resistance in the brachiocephalic arterial tree than in the descending thoracic artery. Blood flow changes in the great arteries determined those in the vena cava superior and inferior.
在对12只麻醉猫进行的实验中，使用电磁血流测量法和模拟计算机来评估硝苯地平和维拉帕米给药后大静脉和动脉血流的变化以及血管阻力的改变。结果表明，这些药物可降低后负荷和静脉回心血量，从而增加心输出量，并使心输出量重新分配，增加脑部供血。这是因为头臂动脉树中的血管阻力比胸降动脉中的血管阻力下降更为明显。大动脉中的血流变化决定了上、下腔静脉中的血流变化。
