Ploncard P
Neurochirurgie. 1976 May-Jun;22(3):253-60.
Impressed by multiplicity of theories and conceptions concerning nerve surgery and by the difficulty to draw grouded conclusions from the different and contradictory work available from the litterature on the subject, the author makes a revision of the biology of the nerve, to be used as a point of departure for investigation. Based on the fact that protheosynthesis capacity of the nerve cell is known to be at its top value during the first week after the lesion of the nerve, the author endeavours to compare immediate suture with delayed suture. This comparative study is based both on electrophysiological and histological data and show clearly enough the real advantage of trying nerve reconstruction as early as possible, to avoid progression of devitalisation and invasion by fibrosis of both stumps. The surgical procedures are made with the help of the operating microscope and the same technique is used in both groups.
鉴于有关神经外科的理论和概念繁多,且难以从该主题文献中不同且相互矛盾的研究得出有充分依据的结论,作者对神经生物学进行了修订,以此作为研究的出发点。基于神经细胞的蛋白质合成能力在神经损伤后的第一周达到峰值这一事实,作者致力于比较一期缝合和二期缝合。这项比较研究基于电生理和组织学数据,清楚地表明了尽早尝试神经重建的实际优势,以避免两断端失活进展和纤维化侵袭。手术操作借助手术显微镜进行,两组采用相同的技术。