Batura-Gabryel H, Firlik M, Wieczorek U
Klinika Pneumonologii Instytutu Chorób Wewnetrznych AM w Poznaniu.
Med Dosw Mikrobiol. 1994;46(1-2):79-81.
The study was aimed at determination of frequency and size of fungal infection in patients with lung carcinoma, as compared with the control group. The study involved 20 patients with histologically confirmed lung carcinoma and--as a control group--20 patients with other lung diseases and healthy volunteers. Quantitative mycological investigation of sputum and bronchial rinsings were performed threefold. The degree of infection of these materials was determined on a Sabouraud medium. Candida-like fungi were determined basing on API 20 AUX test. In majority of patients with lung carcinoma, presence of pathogenic fungi, mostly from the genus Candida, was detected in sputum or bronchial secretions. In one third of cases infection was severe or very severe which was dependent of the stage of disease advancement. In control group severe infection was observed only sporadically.
本研究旨在确定肺癌患者真菌感染的频率和感染规模，并与对照组进行比较。该研究纳入了20例经组织学确诊的肺癌患者，以及20例患有其他肺部疾病的患者和健康志愿者作为对照组。对痰液和支气管冲洗液进行了三次定量真菌学调查。在沙氏培养基上测定这些样本的感染程度。基于API 20 AUX试验鉴定假丝酵母菌样真菌。在大多数肺癌患者的痰液或支气管分泌物中检测到致病真菌的存在，其中大部分来自念珠菌属。在三分之一的病例中，感染严重或非常严重，这取决于疾病进展阶段。在对照组中，仅偶尔观察到严重感染。
