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[单次给予四咪唑后鹧鸪嗜眼吸虫组织的病理变化]

[Pathological changes in the tissues of the helminth Thominx phasianina after the single administration of tetramisole].

作者信息

Chebyshev N V, Shlikas A V, Alekseevskikh Iu G, Suranova T G

出版信息

Med Parazitol (Mosk). 1993 Jul-Sep(4):47-9.

PMID:7968812
Abstract

A single dose (0.2 g/kg) of 20% tetramisole granulate to pheasants infected with Thominx phasianina resulted in intestinal helminth elimination in 72 hours. Structural injuries of the helminth cutaneomuscular sac, digestive and sexual system were detected, manifesting 6 h after the injection and reaching their peak 24 h after it. The mitochondria and endoplasmic reticulum of middle intestinal wall, uterus, oviduct epitheliocytes, oogonia, and oocytes of nematodes were found the most sensitive to the drug.

摘要

对感染雉鸡毛细线虫的雉鸡单次投喂剂量为0.2 g/kg的20%四咪唑颗粒剂,72小时内肠道寄生虫被清除。观察到寄生虫皮肌囊、消化系统和生殖系统的结构损伤,注射后6小时出现,24小时达到峰值。发现线虫中肠壁、子宫、输卵管上皮细胞、卵原细胞和卵母细胞的线粒体和内质网对该药物最为敏感。

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