Biswas A, Arulkumaran S, Ratnam S S
Department of Obstetrics & Gynaecology, National University Hospital, National University of Singapore.
Obstet Gynecol Surv. 1994 Aug;49(8):585-94. doi: 10.1097/00006254-199408000-00027.
No significant change in platelet number, function or life-span occurs during pregnancy. However, pregnancy may be complicated by various platelet abnormalities or platelets may be involved in pregnancy pathologies. Thrombocytopenia is the most common platelet disorder to affect pregnancy. It may occur in a number of clinical conditions and both immune and nonimmune mechanisms may be involved. Apart from the risks to the mother, the fetus may be secondarily affected, especially in cases of immunogenic thrombocytopenia. Management of the mother may not necessarily improve fetal prognosis. Improvement in diagnostic techniques like percutaneous umbilical blood sampling (PUBS) has greatly improved in utero diagnosis and management of the affected fetus. The diagnosis and management of the various platelet disorders affecting the pregnant woman and the fetus are discussed in this overview.
孕期血小板数量、功能或寿命无显著变化。然而，妊娠可能并发各种血小板异常，或者血小板可能参与妊娠病理过程。血小板减少症是影响妊娠最常见的血小板疾病。它可能发生在多种临床情况下，免疫和非免疫机制都可能涉及。除了对母亲有风险外，胎儿可能会受到继发性影响，尤其是在免疫性血小板减少症的情况下。对母亲的治疗不一定能改善胎儿预后。像经皮脐血采样（PUBS）这样的诊断技术的改进，极大地改善了对受影响胎儿的宫内诊断和管理。本综述讨论了影响孕妇和胎儿的各种血小板疾病的诊断和管理。
