Raitta C, Lehto I, Puska P, Vesti E, Harju M
Department of Ophthalmology, University of Helsinki, Finland.
Ophthalmic Surg. 1994 Aug;25(8):536-9.
The effect of injecting sodium hyaluronate (Healon) before fistulization in trabeculectomy was investigated in a prospective, randomized study of 107 consecutive eyes. Fifty-two eyes were operated on with the viscoelastic and 55 without. An early postoperative intraocular pressure (IOP) peak of 21 mm Hg or more occurred in 27% of the study eyes versus 17% of the control eyes, an insignificant difference. The mean peak IOPs of the study and the control eyes did not differ significantly (29.8 +/- 9.0 mm Hg versus 32.7 +/- 10.2 mm Hg), nor did the mean IOPs and the need for glaucoma medications 1 month after surgery. Shallow/flat anterior chamber and choroidal detachment were equally frequent in both groups, but hyphema occurred significantly more often in the study group (40%) than in the control group (18%).
在一项对107只连续眼进行的前瞻性随机研究中，研究了小梁切除术中在造瘘前注射透明质酸钠（Healon）的效果。52只眼使用粘弹性物质进行手术，55只眼未使用。研究组27%的眼术后早期眼压（IOP）峰值达到21 mmHg或更高，而对照组为17%，差异无统计学意义。研究组和对照组的平均眼压峰值无显著差异（29.8±9.0 mmHg对32.7±10.2 mmHg），术后1个月的平均眼压及青光眼药物使用需求也无显著差异。浅/扁平前房和脉络膜脱离在两组中同样常见，但前房积血在研究组（40%）中比对照组（18%）更频繁出现。
