Merksz M, Csontai A, Tóth J
Fövárosi Onkormányzat Heim Pál Gyermekkórház urológiai sebészeti osztály.
Orv Hetil. 1994 Oct 23;135(43):2363-9.
The authors report about their point of view, based on their experience treating children with vesicoureteric reflux (VUR) in the last two decades. 812 children were treated for VUR between 1973-1992. In 62 (7.6%) due to the parenchymal damage, primary nephrectomy was made, antireflux operations were done in 227 (30.3%). Without surgery, recovery or significant improvement was achieved in 523 children (69.7%). The basis of the good results with conservative therapy is in their opinion the thorough knowledge of the function of the urinary organs, especially of the urinary tract, and the precise detection of the pathophysiological processes leading to VUR. The conditions in which antireflux surgery is avoided, are discussed in details, emphasizing the situations and methods eventually leading to mistakes, e. g. the improper judgement of VUR detected during acute pyelonephritis or during an incorrectly performed micturition cystography, and the undiagnosed damaged bladder function. Essential is therefore to clarify the etiology of the VUR and the compensated/uncompensated state of the urinary tract, the clinical condition of the child. Antireflux operation is necessary only if in the renal parenchymal damage the role of the VUR is obvious and it can be prevented only with surgery.
作者基于过去二十年治疗小儿膀胱输尿管反流(VUR)的经验阐述了他们的观点。1973年至1992年间,812名儿童接受了VUR治疗。其中62名(7.6%)因实质损害接受了一期肾切除术,227名(30.3%)接受了抗反流手术。523名儿童(69.7%)未经手术即实现了康复或显著改善。他们认为,保守治疗取得良好效果的基础在于对泌尿器官功能,尤其是尿路功能的深入了解,以及对导致VUR的病理生理过程的精确检测。详细讨论了避免抗反流手术的情况,强调了最终可能导致错误的情形和方法,例如对急性肾盂肾炎期间或排尿性膀胱尿道造影操作不当所检测到的VUR判断不当,以及未诊断出的膀胱功能损害。因此,明确VUR的病因、尿路的代偿/失代偿状态以及儿童的临床状况至关重要。仅当肾实质损害中VUR的作用明显且唯有手术才能预防时,抗反流手术才是必要的。