Schneider P, Börner W
Klinik und Poliklinik für Nuklearmedizin, University of Würzburg, FRG.
Nuklearmedizin. 1994 Aug;33(4):138-43.
Results of bone density measurements by quantitative computed tomography of the peripheral skeleton (pQCT) were compared with those of measurements at the axial skeleton with a view to study the effects of degenerative spinal changes on the validity of bone densitometry of the lumbar spine. 556 consecutive patients were examined by dual-energy x-ray absorptiometry (DXA) of the spine and by peripheral quantitative computed tomography (pQCT) of the distal radius. There were significant differences between the bone mineral values at the distal radius and those at the spine, depending on the degree of spinal degeneration. As expected, spinal degenerations showed a highly significant age dependence. With increasing degeneration the correlations between the radius total bone mineral concentration and the bone density of the lumbar spine decreased from r = 0.45 to 0.23 in women and from r = 0.64 to 0.28 in men. We conclude that the value of spinal DXA is reduced in patients with degenerative spinal disease, compared to the pQCT at the peripheral skeleton.
为了研究脊柱退变对腰椎骨密度测定有效性的影响，对外周骨骼定量计算机断层扫描（pQCT）的骨密度测量结果与轴向骨骼的测量结果进行了比较。对556例连续患者进行了脊柱双能X线吸收法（DXA）和桡骨远端外周定量计算机断层扫描（pQCT）检查。根据脊柱退变程度，桡骨远端和脊柱的骨矿物质值存在显著差异。正如预期的那样，脊柱退变显示出高度显著的年龄依赖性。随着退变程度的增加，女性桡骨总骨矿物质浓度与腰椎骨密度之间的相关性从r = 0.45降至0.23，男性从r = 0.64降至0.28。我们得出结论，与外周骨骼的pQCT相比，脊柱退变疾病患者的脊柱DXA值降低。
