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[嗜酸性粒细胞在过敏反应和支气管哮喘中的作用的一些现代观点以及一种检测支气管分泌物中嗜酸性粒细胞的新方法]

[Some modern views of the role of the eosinophils in allergic reactions and bronchial asthma and a new method of detecting eosinophils in the bronchial secretion].

作者信息

Denchev K, Lipcheva N, Kis'ova K

出版信息

Vutr Boles. 1976;15(5):66-72.

PMID:797138
Abstract

A review of certain contemporary opinions of eosinophil function in allergic reactions and bronchial asthma is presented in this report. Phagocytosis and processing of the complexes antigenantibody, histamine inhibition and a histamine elimination elimination by a specific inhibitor, isolated from eosinophilis (EDI), stimulation of prostaglandines E release, which also inhibit histamine and have a bronchial dilataion effect. The new method is recommended for eosinophil detection in sputa based on the fluorescent principle as faster and more efficient.

摘要

本报告综述了当前关于嗜酸性粒细胞在过敏反应和支气管哮喘中作用的某些观点。包括吞噬和处理抗原抗体复合物、组胺抑制作用以及通过从嗜酸性粒细胞中分离出的一种特异性抑制剂(EDI)消除组胺、刺激前列腺素E释放(其也抑制组胺并具有支气管扩张作用)。基于荧光原理的痰液嗜酸性粒细胞检测新方法被推荐,因为它更快且更有效。

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