Salomon P, Mazurek W
Katedry i Kliniki Kardiologii Akademii Medycznej we Wrocławiu.
Pol Arch Med Wewn. 1994 Jun;91(6):446-50.
Plasma beta-endorphin levels were estimated in patients with painless myocardial ischaemia. The survey was made in 90 patients with coronary artery disease: 55 of them after myocardial infarction and 35 with chronic stable angina pectoris. The control group comprised 22 healthy persons. Plasma beta-endorphin level was determined in all examined patients immediately before the exercise test, just after finishing exercise test, and 6 minutes after the termination of the exercise test. Beta-endorphin plasma levels has been determined with a radioimmunologic method by the means of "beta-endorphins [125J]RIA Kit" manufactured in NEN Research Products. Study showed that in the patients with silent myocardial ischaemia plasma beta-endorphin level was higher than in patients with painful myocardial ischaemia both at rest during exercise test. Increase of plasma beta-endorphin in examined patients can be one of etiopathogenetic factors of silent myocardial ischaemia.
对无痛性心肌缺血患者的血浆β-内啡肽水平进行了评估。该调查针对90例冠心病患者展开：其中55例为心肌梗死后患者，35例为慢性稳定型心绞痛患者。对照组由22名健康人组成。在所有接受检查的患者中，于运动试验前即刻、运动试验结束后即刻以及运动试验终止6分钟后测定血浆β-内啡肽水平。采用放射免疫法，借助NEN研究产品公司生产的“β-内啡肽[125I]放射免疫分析试剂盒”测定血浆β-内啡肽水平。研究表明，在静息及运动试验期间，无症状性心肌缺血患者的血浆β-内啡肽水平均高于有症状性心肌缺血患者。受检患者血浆β-内啡肽水平升高可能是无症状性心肌缺血的病因学因素之一。
