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[关于血清肌红蛋白水平对急性心肌梗死患者再灌注诊断的有用性的测试]

[Tests concerning the usefulness of serum myoglobin levels for the diagnosis of reperfusion in patients with imminent myocardial infarction].

作者信息

Haczyński J, Kucharski W

机构信息

Katedry i Kliniki Kardiologii AM we Wrocławiu.

出版信息

Pol Tyg Lek. 1993;48(31-33):692-3.

PMID:7971491
Abstract

Blood myoglobin, CPK and CK-MB activities were assayed in 32 patients with the acute myocardial infarction up to 360 minutes following the start of thrombolytic therapy. Plasma myoglobin, CPK and CK-MB activities increased significantly less in 18 patients in whom reperfusion of the coronary artery has been noted. Maximum increase in myoglobin levels preceded an increase in CPK and CK-MB activities and it may be an early marker of reperfusion.

摘要

在32例急性心肌梗死患者溶栓治疗开始后长达360分钟的时间内,检测了其血液中的肌红蛋白、肌酸磷酸激酶(CPK)及肌酸激酶同工酶(CK-MB)活性。在18例已观察到冠状动脉再灌注的患者中,血浆肌红蛋白、CPK及CK-MB活性的显著升高幅度较小。肌红蛋白水平的最大升高先于CPK及CK-MB活性的升高,它可能是再灌注的早期标志物。

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