氟达拉滨治疗慢性淋巴细胞白血病后发生的肿瘤溶解综合征
Tumour lysis syndrome after treatment of chronic lymphocytic leukaemia with fludarabine.
作者信息
Montalban C, Liaño F, Aguilera A
机构信息
Department of Internal Medicine, Hospital Ramón y Cajal, Universidad de Alcalá de Henares, Madrid, Spain.
出版信息
Postgrad Med J. 1994 Sep;70(827):651-2. doi: 10.1136/pgmj.70.827.651.
Abstract
Fludarabine is one of the most recent and promising therapeutic agents for chronic lymphocytic leukaemia. We describe a patient who developed tumour lysis syndrome after the first course of treatment with fludarabine and call attention to this uncommon but potentially lethal complication that has not been previously taken into account in this neoplasia. It should always be anticipated when patients are treated with new and effective drugs.
摘要
氟达拉滨是治疗慢性淋巴细胞白血病的最新且最有前景的治疗药物之一。我们描述了一名患者，其在接受首个疗程的氟达拉滨治疗后发生了肿瘤溶解综合征，并提醒注意这种在该肿瘤中未被先前考虑到的罕见但可能致命的并发症。在使用新的有效药物治疗患者时应始终对此有所预见。
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