Jørgensen P
Department A, Psychiatric Hospital in Aarhus, Risskov, Denmark.
Psychopathology. 1994;27(1-2):79-88. doi: 10.1159/000284852.
A study sample of 88 delusional patients has been examined prospectively from first admission and during three personal follow-up sessions. After 8 years of observation, the diagnostic distribution is presented according to the ICD-10 and the DSM-III-R classification systems, among which a large degree of agreement is found. Schizophrenia turned out to be the most frequent diagnosis but almost half of the patients belong to another diagnostic category. Diagnostic assignment was changed in only a few patients when compared to the time of discharge after the first admission. From the time of index admission, the patients' preceding course and global functioning differ. A major finding is the fact that in general short-term course and outcome are very similar to those of medium-term observation. Forty-three per cent of the patients still alive remained delusional throughout the observation period. Delusional beliefs do not persist in all patients with the diagnosis of persistent delusional disorder. Most patients with continuous delusional beliefs belong to the diagnostic category of schizophrenia. Global assessment functioning at 8-year follow-up is: schizophrenia, 35; affective disorder, 82; persistent delusional disorder, 50, and acute and transient psychotic disorder, 72.
对88名妄想症患者的研究样本进行了前瞻性研究，从首次入院开始，并在三次个人随访期间进行观察。经过8年的观察，根据ICD - 10和DSM - III - R分类系统呈现诊断分布情况，发现两者之间有很大程度的一致性。结果显示精神分裂症是最常见的诊断，但几乎一半的患者属于其他诊断类别。与首次入院出院时相比，只有少数患者的诊断有所改变。从首次入院时起，患者之前的病程和整体功能就有所不同。一个主要发现是，总体而言，短期病程和结果与中期观察结果非常相似。在整个观察期内，仍存活的患者中有43%一直存在妄想。并非所有被诊断为持续性妄想障碍的患者都会持续存在妄想信念。大多数持续存在妄想信念的患者属于精神分裂症诊断类别。8年随访时的整体功能评估结果为：精神分裂症患者为35，情感障碍患者为82，持续性妄想障碍患者为50，急性和短暂性精神病性障碍患者为72。
