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[放疗治疗脑动静脉畸形的时间飞跃磁共振血管造影术]

[TOF-MR angiography in radiotherapy treated cerebral arteriovenous malformations].

作者信息

Schlemmer H P, Hess T, Debus J, Knopp M V, Schad L R, Engenhart R

机构信息

Forschungsschwerpunkt Radiologische Diagnostik und Therapie, Deutsches Krebsforschungszentrum, Heidelberg.

出版信息

Radiologe. 1994 Aug;34(8):447-53.

PMID:7972722
Abstract

Intracerebral arteriovenous malformations represent congenital anomalies with an arteriovenous shunt (nidus). The therapeutic goal is to eliminate the risk of bleeding and to improve the clinical symptoms. The exact localization of the nidus and the identification of the feeding arteries are critical for therapy planning. Up to now conventional brain angiograms have been used for treatment planning and for the assessment of therapy response. We studied whether 3D time-of-flight (TOF) MR angiography can be used for therapy planning and monitoring. MRI and TOF-MRA studies of 28 patients undergoing radiotherapy were evaluated. They were compared to conventional angiography to assess the MRA study. A Correct identification of the arterial feeder and the nidus was possible in about 75% of the patients. In combination with the MRI study, an important 3D dataset for treatment planning could be obtained that includes therapeutically relevant information on the localization and spatial structure of the AVM as well as the adjacent brain tissue. As a noninvasive technique, close-meshed follow-up studies could be performed with MRA.

摘要

脑动静脉畸形是一种带有动静脉分流(病灶)的先天性异常。治疗目标是消除出血风险并改善临床症状。病灶的确切定位以及供血动脉的识别对于治疗方案规划至关重要。到目前为止,传统脑血管造影一直用于治疗方案规划和治疗反应评估。我们研究了三维时间飞跃(TOF)磁共振血管造影是否可用于治疗方案规划和监测。对28例接受放射治疗患者的MRI和TOF-MRA研究进行了评估。将其与传统血管造影进行比较以评估MRA研究。在大约75%的患者中能够正确识别动脉供血和病灶。结合MRI研究,可以获得一个重要的三维数据集用于治疗方案规划,其中包括有关动静脉畸形定位和空间结构以及相邻脑组织的治疗相关信息。作为一种无创技术,MRA可用于进行密集的随访研究。

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